Four-leaf Milkweed
Asclepias quadrifolia
Last reviewed: June 2026
Four-leaf Milkweed is toxic to dogs and cats.
Listed as toxic by the ASPCA Animal Poison Control Center (last reviewed 2026-05-21). If your pet has been exposed, call the ASPCA Animal Poison Control Center at (888) 426-4435and your veterinarian's emergency line.
Pollinator Patch flags toxic plants so you can choose a pet-safe native alternative for your yard.
Light
part sun
Water
medium
Size
12"–24" H × 6"–12" W
Bloom
Jun, Jul
Native to
AL, AR, CT, DE and 23 more states
Pollinators
bees, butterflies, moths
Four-leaf milkweed is a compact native perennial with distinctive whorled leaves and small clusters of pale pink or white flowers in early summer. This smaller milkweed species forms neat clumps and works well in partially shaded areas where other milkweeds might struggle.
In an HOA neighborhood
Four-leaf Milkweed is an HOA-friendly choice. Maintenance level: low. Tidiness: 3 out of 5.
Works well in: foundation, mid zone, backyard only.
- Dies back completely in winter
- May need education about milkweed benefits
- Flowers are small and subtle
Wildlife value
Host plant for monarch butterfly, queen butterfly.
Essential host plant for monarch butterfly caterpillars and provides nectar for various native bees, butterflies, and moths. Its compact size makes it ideal for pollinator gardens in smaller spaces.
Native range data from the USDA PLANTS Database and regional native plant society lists. Pollinator and host plant associations compiled from GBIF, iNaturalist, and published ecological literature.
Pollinator Patch flags toxic plants like Four-leaf Milkweed and shows pet-safe natives for your ecoregion instead.